Duffy J D, Campbell J J
Allegheny Neuropsychiatric Institute, Oakdale, Pennsylvania.
J Neuropsychiatry Clin Neurosci. 1994 Fall;6(4):379-87. doi: 10.1176/jnp.6.4.379.
This article provides a broad theoretical and clinical overview of the three regional prefrontal syndromes. An understanding of the extended neural connectivity of the prefrontal cortex provides the template for describing the three distinct prefrontal syndromes (dysexecutive, disinhibited, and apathetic types), each associated with dysfunction in one of the three prefrontal regions. This clinical approach should aid the clinician in determining the etiology of the specific regional prefrontal syndrome and developing effective treatment strategies.
本文对三种区域性前额叶综合征进行了广泛的理论和临床概述。对前额叶皮质扩展神经连接性的理解为描述三种不同的前额叶综合征（执行功能障碍型、去抑制型和冷漠型）提供了模板，每种综合征都与三个前额叶区域之一的功能障碍相关。这种临床方法应有助于临床医生确定特定区域性前额叶综合征的病因并制定有效的治疗策略。
