Armstrong M
Microbiology Department, Central Manchester Health Care Trust, Manchester Royal Infirmary, England, UK.
Br J Biomed Sci. 1994 Mar;51(1):65-72.
Microbial keratitis is an infectious inflammation of the cornea which, if not rapidly diagnosed, may lead to loss of vision. The investigative procedures are demanding for the ophthalmologist and confirmative diagnosis a formidable challenge to the microbiologist. Most, if not all, bacteria can cause keratitis. To establish a diagnosis culture is essential, since it is not possible clinically to distinguish between one type of infective keratitis and another. A relatively new and worrying problem is acanthamoebic keratitis, which is significantly associated with contact lens wear. It is increasing in incidence as lens wear becomes more popular. Although Acanthamoebae are easily isolated, many laboratories are not familiar with laboratory methods for diagnosis.
微生物性角膜炎是一种角膜感染性炎症，若不迅速诊断，可能导致视力丧失。对于眼科医生而言，检查程序要求颇高，而确诊对微生物学家来说是一项艰巨的挑战。大多数（即便不是全部）细菌都可引发角膜炎。要确诊，培养至关重要，因为临床上无法区分不同类型的感染性角膜炎。一个相对较新且令人担忧的问题是棘阿米巴角膜炎，它与隐形眼镜佩戴密切相关。随着隐形眼镜佩戴愈发普遍，其发病率正在上升。尽管棘阿米巴很容易分离出来，但许多实验室并不熟悉其诊断的实验室方法。
