Machida K, Honda N, Mamiya T, Takahashi T, Kamano T, Kashimada A, Inoue Y, Kinoshita M
Department of Radiology, Saitama Medical Center, Saitama Medical School, Japan.
Clin Nucl Med. 1994 Nov;19(11):968-72. doi: 10.1097/00003072-199411000-00006.
Iodine-123 MIBG is a norepinephrine analog which can be used to image the sympathetic innervation of the heart. The authors report a patient with myotonic dystrophy whose I-123 MIBG SPECT revealed accelerated washout of I-123 MIBG from infero-posterior and a part of lateral wall, although Tl-201 SPECT showed no abnormal finding. The authors conclude that I-123 MIBG can be more sensitive in detecting the cardiac abnormality than Tl-201 SPECT in this disease.
碘-123间碘苄胍（I-123 MIBG）是一种去甲肾上腺素类似物，可用于对心脏的交感神经支配进行成像。作者报告了一名患有强直性肌营养不良的患者，其I-123 MIBG单光子发射计算机断层扫描（SPECT）显示下后壁和部分侧壁的I-123 MIBG洗脱加速，尽管铊-201（Tl-201）SPECT未显示异常发现。作者得出结论，在这种疾病中，I-123 MIBG在检测心脏异常方面比Tl-201 SPECT更敏感。
