Marumo K, Homma S, Fukuchi Y
Department of Internal Medicine, Tokyo Metropolitan Police Hospital, Japan.
Chest. 1995 Feb;107(2):453-6. doi: 10.1378/chest.107.2.453.
One hundred eighty-six patients who had undergone total gastrectomy were analyzed in regard to pulmonary aspiration. Sixteen patients (8.6%) with recurrent respiratory tract inflammation (r-RTI) and 45 patients (24.2%) with sporadic RTI (s-RTI) were observed. The r-RTI group frequently showed symptoms related to esophageal reflux among the many factors affecting the onset of disease. They were also characterized by marked inflammatory responses with various and atypical clinical courses. The swallowing provocation test showed swallowing disturbances (prolonged latency) in patients with r-RTI. We concluded that the aspiration of esophageal reflux contents was the most important risk factor of recurrent pulmonary complications in patients with total gastrectomy.
对186例行全胃切除术的患者进行了关于肺误吸的分析。观察到16例(8.6%)患有复发性呼吸道炎症(r-RTI)的患者和45例(24.2%)患有散发性RTI(s-RTI)的患者。在影响疾病发生的诸多因素中,r-RTI组经常出现与食管反流相关的症状。它们还具有明显的炎症反应以及多样和非典型的临床病程的特点。吞咽激发试验显示r-RTI患者存在吞咽障碍(潜伏期延长)。我们得出结论,食管反流物的误吸是全胃切除患者复发性肺部并发症的最重要危险因素。