Wang H Y, Li H Z, Zhao Y P
Institute of Occupational Medicine, Ministry of Coal Industry, Beijing.
Zhonghua Yu Fang Yi Xue Za Zhi. 1994 May;28(3):164-6.
Dust deposition in the lung tissue of 10 cases with pathologically diagnosed stage I CWP was determined. The left lung tissue was digested by 37% hydrochloric acid, and its organic composition was removed by chloroform and 50% ethanol. Results showed total dust content averaged 8.64 grams per left lung, with a standard deviation of 5.54 grams. Dust content varied in different parts of the lung, measured the highest in lymph nodes, the upper lobe and pleura the next and the lowest in the lower lobe, with a very significant difference by ANOVA (F = 44.76, P < 0.001). Dust less than 5 microns in diameter accounted for 94.0% of the total content, and that equal to or more than 10 microns only 0.8%. A certain amount of fibrous dust could be found in the lung. Dust deposited in the lung accounted only for 0.64% of that exposed to.
对10例经病理诊断为I期煤工尘肺(CWP)患者的肺组织进行了粉尘沉积测定。左肺组织用37%盐酸消化,其有机成分用氯仿和50%乙醇去除。结果显示,左肺粉尘总含量平均为8.64克,标准差为5.54克。肺不同部位的粉尘含量不同,淋巴结中测得的粉尘含量最高,上叶和胸膜次之,下叶最低,经方差分析差异非常显著(F = 44.76,P < 0.001)。直径小于5微米的粉尘占总含量的94.0%,直径等于或大于10微米的仅占0.8%。在肺中可发现一定量的纤维性粉尘。沉积在肺中的粉尘仅占接触粉尘量的0.64%。