Yu L X, Bai X W, Wang J Y
Renal Transplantation Center, Nanfang Hospital, First Military Medical University, Guangzhou.
Zhonghua Wai Ke Za Zhi. 1994 Jun;32(6):348-50.
156 patients received renal transplantation in the Nanfang Hospital from October 1992 to December 1993. 27 patients developed refractory acute rejection (RAR). Of them, rejection was reversed completely with lymphogloline (ATG) in 22 patients and reversed with OKT3 in 4. One patient died of cerebral hemorrhage after removal of the donor's kidney. The results suggest that ATG is safe, effective, highly specific, sensitive, and of less side-effect. The pathogenesis, diagnosis of RAR and cautions for ATG are discussed.
1992年10月至1993年12月期间，156例患者在南方医院接受了肾移植手术。27例患者发生了难治性急性排斥反应（RAR）。其中，22例患者使用抗淋巴细胞球蛋白（ATG）后排斥反应完全逆转，4例患者使用OKT3后逆转。1例患者在摘除供肾后死于脑出血。结果表明，ATG安全、有效、特异性高、敏感性强且副作用小。文中讨论了RAR的发病机制、诊断及使用ATG的注意事项。
