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心肝核素比值在肝硬化门静脉高压症中的诊断价值

[Diagnostic value of heart-liver nuclein ratio in cirrhotic portal hypertension].

作者信息

Chen F Z, Xu W G, Wang J Y

机构信息

Zhongshan Hospital, Shanghai Medical University.

出版信息

Zhonghua Wai Ke Za Zhi. 1994 Jul;32(7):395-7.

PMID:7842972
Abstract

A new method for evaluating portal systemic collaterals with administering 99mTc-MIBI per rectum was described in 80 cases. The heart to liver uptake ratio (H/L) in 15 healthy subjects was 0.267 +/- 0.1, slightly increased (0.455 +/- 0.13) in 8 patients with viral hepatitis and significantly increased in 68 cirrhotics. There was a good correlation between H/L ratio and the Child-Pugh classification with the ratio in Child A group of 0.57 +/- 0.12, in Child B group of 1.0 +/- 0.19, and in Child C group of 1.19 +/- 0.25 respectively (P < 0.01). For the diagnosis of portal hypertension, tentatively taking the ratio of > or = 0.62 as positive the sensitivity was 96%, specificity 89%, and accuracy 94%. The authors believe that 99mTc-MIBI imaging is a noninvasive method very useful in evaluating porta-systemic shunts.

摘要

本文描述了一种通过经直肠给予99mTc-MIBI来评估门体侧支循环的新方法,共纳入80例患者。15名健康受试者的肝心摄取比(H/L)为0.267±0.1,8例病毒性肝炎患者的该比值略有升高(0.455±0.13),68例肝硬化患者的该比值显著升高。H/L比值与Child-Pugh分级之间存在良好相关性,Child A组的比值为0.57±0.12,Child B组为1.0±0.19,Child C组为1.19±0.25(P<0.01)。对于门静脉高压的诊断,暂定以≥0.62为阳性,其敏感性为96%,特异性为89%,准确性为94%。作者认为,99mTc-MIBI显像术是一种评估门体分流非常有用的非侵入性方法。

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