Chen F Z, Xu W G, Wang J Y
Zhongshan Hospital, Shanghai Medical University.
Zhonghua Wai Ke Za Zhi. 1994 Jul;32(7):395-7.
A new method for evaluating portal systemic collaterals with administering 99mTc-MIBI per rectum was described in 80 cases. The heart to liver uptake ratio (H/L) in 15 healthy subjects was 0.267 +/- 0.1, slightly increased (0.455 +/- 0.13) in 8 patients with viral hepatitis and significantly increased in 68 cirrhotics. There was a good correlation between H/L ratio and the Child-Pugh classification with the ratio in Child A group of 0.57 +/- 0.12, in Child B group of 1.0 +/- 0.19, and in Child C group of 1.19 +/- 0.25 respectively (P < 0.01). For the diagnosis of portal hypertension, tentatively taking the ratio of > or = 0.62 as positive the sensitivity was 96%, specificity 89%, and accuracy 94%. The authors believe that 99mTc-MIBI imaging is a noninvasive method very useful in evaluating porta-systemic shunts.
本文描述了一种通过经直肠给予99mTc-MIBI来评估门体侧支循环的新方法，共纳入80例患者。15名健康受试者的肝心摄取比（H/L）为0.267±0.1，8例病毒性肝炎患者的该比值略有升高（0.455±0.13），68例肝硬化患者的该比值显著升高。H/L比值与Child-Pugh分级之间存在良好相关性，Child A组的比值为0.57±0.12，Child B组为1.0±0.19，Child C组为1.19±0.25（P<0.01）。对于门静脉高压的诊断，暂定以≥0.62为阳性，其敏感性为96%，特异性为89%，准确性为94%。作者认为，99mTc-MIBI显像术是一种评估门体分流非常有用的非侵入性方法。
