Gong X, Shao M, Tao X, Wei L, Dai Z
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, China.
Yan Ke Xue Bao. 1994 Jun;10(2):90-3.
A quantitative analysis of corneal endothelial cells was made with photoelectrical scans and computer in 67 eyes. No difference was found as regards to the mean cell area and density between the endothelial analysis system and routine square counting. On the other hand, we analyzed corneal endothelial cells between 30 eyes wearing hard contact lens and 30 eyes of age- and sex-matched nonwearing control. The parameters, including cell density individual cell area, area, mean cell area, standard deviation, coefficient of variation of cell size (CV), maximum cell, minimum cell, the ratio of the maximum to minimum cell, and percentage of the hexagoal cells, were automatically displayed. The cell density and mean cell area also showed no significant difference (P > 0.05) between the wearers and nonwearing control, but the CV and the frequency of the hexagonal cells showed significant difference (P < 0.01). The ratio of maximum to minimum cell, the polymegethism and pleomorphism were obviously increased in the wearers. It is highly suggested that computer analysis system is of great value in evaluating corneal endothelial cells.
采用光电扫描和计算机技术对67只眼的角膜内皮细胞进行了定量分析。在内皮分析系统和常规方格计数法之间，平均细胞面积和密度方面未发现差异。另一方面，我们对30只佩戴硬性隐形眼镜的眼睛和30只年龄及性别匹配的未佩戴隐形眼镜的对照眼睛的角膜内皮细胞进行了分析。自动显示了包括细胞密度、单个细胞面积、面积、平均细胞面积、标准差、细胞大小变异系数（CV）、最大细胞、最小细胞、最大与最小细胞之比以及六边形细胞百分比等参数。佩戴者和未佩戴者对照组之间的细胞密度和平均细胞面积也无显著差异（P>0.05），但CV和六边形细胞频率有显著差异（P<0.01）。佩戴者的最大与最小细胞之比、大小不均一性和多形性明显增加。强烈建议计算机分析系统在评估角膜内皮细胞方面具有重要价值。
