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[转移性恶性睾丸畸胎瘤中的荨麻疹性血管炎综合征]

[Urticaria-vasculitis syndrome in metastatic malignant testicular teratoma].

作者信息

Sprossmann A, Müller R P

机构信息

Dermatologische Klinik, Klinikum Lippe-Lemgo.

出版信息

Hautarzt. 1994 Dec;45(12):871-4. doi: 10.1007/s001050050189.

DOI:10.1007/s001050050189
PMID:7843969
Abstract

We report on the case history of a 30-year-old man with chronic, therapy-resistant urticarial vasculitis for more than 1 year. On clinical examination a metastasizing malignant teratoma of the testes was diagnosed. For surgical management and oncological therapy the patient was referred to appropriate clinical units. After the treatment there urticarial vasculitis also disappeared without any specific therapy, but the persisting metastases in the lungs caused early reappearance of the urticarial vasculitis. Chemotherapy led to partial remission of metastases, and in fact also to an improvement in the urticarial alterations of the skin. Two months after the last cycle of chemotherapy metastases of the brain were discovered and at the same time the urticarial vasculitis was found to be present again in full-blown form.

摘要

我们报告了一名30岁男性的病史,他患有慢性、对治疗耐药的荨麻疹性血管炎超过1年。临床检查诊断为睾丸转移性恶性畸胎瘤。为进行手术治疗和肿瘤治疗,该患者被转诊至相应的临床科室。治疗后,荨麻疹性血管炎在未进行任何特殊治疗的情况下也消失了,但肺部持续存在的转移灶导致荨麻疹性血管炎早期复发。化疗使转移灶部分缓解,实际上也改善了皮肤的荨麻疹样改变。在最后一个化疗周期两个月后,发现了脑转移,同时荨麻疹性血管炎再次以全面发作的形式出现。

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Urticarial vasculitis in northern Spain: clinical study of 21 cases.西班牙北部的荨麻疹性血管炎:21例临床研究
Medicine (Baltimore). 2014 Jan;93(1):53-60. doi: 10.1097/MD.0000000000000013.