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腹部扩张作为IV-S期神经母细胞瘤伴巨大肝肿大的一种过渡技术。

Abdominal expansion as a bridging technique in stage IV-S neuroblastoma with massive hepatomegaly.

作者信息

Lee E W, Applebaum H

机构信息

Department of Surgery, Kaiser Permanente Medical Center, Los Angeles, CA 90027.

出版信息

J Pediatr Surg. 1994 Nov;29(11):1470-1. doi: 10.1016/0022-3468(94)90146-5.

Abstract

Stage IV-S neuroblastoma has a relatively favorable outcome. However, urgent surgical treatment may be necessary for management of life-threatening complications related to massive hepatomegaly caused by metastatic tumor infiltration. The enlarged liver often becomes of primary concern because diaphragmatic elevation results in life-threatening respiratory embarrassment. An external SILAS-TIC dome has been used as a temporizing procedure to decrease the intraabdominal pressure. The authors developed a modification of this approach using an internal polytetrafluoroethylene patch to create a ventral hernia. This technique decreases the potential complications of prosthetic material use, namely, risk of infection. The graft may be left in place for an extended period and removed in staged operations as the bulk of the metastatic tumor regresses.

摘要

IV-S期神经母细胞瘤的预后相对较好。然而,对于因转移性肿瘤浸润导致的巨大肝肿大相关的危及生命的并发症,可能需要紧急手术治疗。肿大的肝脏常常成为首要关注对象,因为膈肌抬高会导致危及生命的呼吸窘迫。外部的SILAS-TIC穹顶已被用作一种临时措施来降低腹内压。作者对这种方法进行了改良,使用内部聚四氟乙烯补片来制造腹疝。该技术降低了使用假体材料的潜在并发症,即感染风险。移植物可长期留置,并在分期手术中随着转移性肿瘤大部分消退而取出。

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