Eisenmann D, Jacobi K W, Krzizok T, Reiner J
Universitäts-Augenklinik Giessen.
Klin Monbl Augenheilkd. 1994 Nov;205(5):289-97. doi: 10.1055/s-2008-1045531.
The optic of common multifocal IOLs (MIOLs) is effecting an even light distribution to far and near focus. New MIOL designs were developed by Jacobi to improve distance or near contrast, by favouring the far or near focus with 60-70% of the light energy. For binocular implantation, an "asymmetrical" MIOL-combination is possible with accentuation of distance focus in one eye and near focus in the other eye.
By means of an optical system described by Jacobi and Reiner "artificial eyes" with the new MIOLs were implanted in 7 young healthy subjects and contrast sensitivity was measured for distance and near. Clinical implantation was performed in 46 patients and visual acuity, contrast sensitivity, depth of focus and binocular functions were determined after 6 months.
MIOL designs with accentuation of distance vision did not show a significant reduction of distance contrast compared with a monofocal IOL. Asymmetrical binocular implantation of the new lenses resulted in a better distance and near contrast sensitivity than implantation of MIOLs with an even light distribution. Binocular functions were not impaired.
Asymmetrical implantation of the new MIOLs with uneven light distribution to far and near focus enables distance vision comparable to monofocal IOLs, but with the advantage of an increased depth of focus.
常见多焦点人工晶状体（MIOL）的光学系统可实现远近焦点的均匀光分布。雅可比开发了新的MIOL设计，通过将60%-70%的光能偏向远焦点或近焦点，来改善远距或近距对比度。对于双眼植入，可采用“不对称”MIOL组合，即一只眼睛突出远焦点，另一只眼睛突出近焦点。
借助雅可比和赖纳描述的光学系统，将植入新MIOL的“人工眼”植入7名年轻健康受试者体内，并测量其远距和近距对比敏感度。对46例患者进行临床植入，6个月后测定其视力、对比敏感度、焦深和双眼功能。
与单焦点人工晶状体相比，突出远视力的MIOL设计在远距对比度上并未显著降低。新型晶状体的不对称双眼植入比均匀光分布的MIOL植入产生了更好的远距和近距对比敏感度。双眼功能未受损害。
对新的MIOL进行远近焦点光分布不均的不对称植入，可实现与单焦点人工晶状体相当的远视力，但具有增加焦深的优势。
