Reinhard T, Sundmacher R
Augenklinik der Heinrich-Heine-Universität Düsseldorf.
Klin Monbl Augenheilkd. 1994 Nov;205(5):305-8. doi: 10.1055/s-2008-1045534.
Peripheral ectasia of the cornea is a rare, but rather complicated form of keratoconus, which in its severest form cannot be corrected by glasses or contact lenses. Penetrating corneal grafts must be positioned directly at the limbus. Such transplants mostly fail because of a high risk of immune reactions which can only be circumvented by systemic Ciclosporin A. To avoid the potential risks of such a systemic immunomodulation we performed instead of a penetrating keratoplasty a special lamellar procedure which restored the normal configuration of the cornea.
The 35-year-old man presented with best corrected visual acuity of 0.1 in both eyes. Contact lenses were not tolerated any longer.
After lamellar dissection, thermoplasty and lamellar horse-shoe sclerokeratoplasty the patient now wears well-fitting contact lenses and has a visual acuity of 0.8 with his right and 0.5 with his left eye after a follow-up period of 25 and 14 months respectively. There were no postoperative complications.
Lamellar horse-shoe sclerokeratoplasty preceded by lamellar corneal dissection and thermoplasty is a technically difficult, but efficient surgical measure to restore the normal corneal curvature in patients with advanced peripheral ectasia of the cornea.
角膜周边扩张是圆锥角膜一种罕见但相当复杂的形式,其最严重的形式无法通过眼镜或隐形眼镜矫正。穿透性角膜移植必须直接置于角膜缘。此类移植大多因免疫反应风险高而失败,而全身使用环孢素A才能规避这种风险。为避免这种全身免疫调节的潜在风险,我们未进行穿透性角膜移植,而是实施了一种特殊的板层手术,恢复了角膜的正常形态。
该35岁男性双眼最佳矫正视力均为0.1。已无法耐受隐形眼镜。
经过板层剖切、热成形术和板层马蹄形巩膜角膜移植术后,患者现在佩戴合适的隐形眼镜,分别随访25个月和14个月后,右眼视力为0.8,左眼视力为0.5。无术后并发症。
在板层角膜剖切和热成形术之后进行板层马蹄形巩膜角膜移植术,是恢复晚期角膜周边扩张患者角膜正常曲率的一项技术难度大但有效的手术措施。