Révész T, Mpofu C, Oyejide C
Department of Paediatrics, Faculty of Medicine and Health Sciences, UAE University.
Leukemia. 1995 Jan;9(1):189-93.
Tawam Hospital is the major paediatric oncology referral centre in the UAE. During the past 11 years, 352 patients (0-12 years of age) were diagnosed to have a childhood malignancy. Leukaemia and lymphoma accounted for 62.7% of all tumours. Stage distribution for Hodgkin's disease (HD) and non-Hodgkin's lymphoma (NHL) showed a relatively high proportion of advanced stage disease. Histological analysis demonstrated a preponderance of lymphocyte predominance and mixed cellularity cases in Hodgkin's disease, and 2/3 of the NHL patients had small, non-cleaved cell lymphoma. Children fell into three main ethnic groups based on the origin/nationality of their parents: Group 1: UAE nationals and Omanis; Group 2: other Arabs; Group 3: Indian/Pakistani (subcontinental) origin. When compared for the relative proportion of leukaemia/lymphoma/other tumours, children of subcontinental origin had significantly more acute lymphoblastic leukaemia (ALL) and less lymphoma than the other two ethnic groups. This is probably due to the higher level of education and smaller family size in group 3 and lends support to the proposed infectious aetiology in ALL.
塔瓦姆医院是阿联酋主要的儿科肿瘤转诊中心。在过去11年中，352名0至12岁的患者被诊断患有儿童恶性肿瘤。白血病和淋巴瘤占所有肿瘤的62.7%。霍奇金病（HD）和非霍奇金淋巴瘤（NHL）的分期分布显示晚期疾病比例相对较高。组织学分析表明，霍奇金病中淋巴细胞为主型和混合细胞型病例占优势，2/3的NHL患者患有小无裂细胞淋巴瘤。根据父母的出身/国籍，儿童分为三个主要种族群体：第1组：阿联酋国民和阿曼人；第2组：其他阿拉伯人；第3组：印度/巴基斯坦（次大陆）血统。在比较白血病/淋巴瘤/其他肿瘤的相对比例时，次大陆血统的儿童急性淋巴细胞白血病（ALL）明显多于其他两个种族群体，淋巴瘤则少于其他两个种族群体。这可能是由于第3组的教育水平较高和家庭规模较小，支持了ALL中提出的感染病因学。
