Maitz P K, Pribaz J J, Hergrueter C A
Division of Plastic Surgery, Brigham and Women's Hospital, Boston, MA 02115.
Microsurgery. 1994;15(9):624-9. doi: 10.1002/micr.1920150904.
As flap prefabrication becomes a more commonly used clinical tool, it is necessary to investigate the limitations of this technique. Reconstructive procedures of the face often require "custom fitted" flaps to satisfy esthetic demands. This study examines and compares the safety of manipulating thin prefabricated skin flaps versus established axial pattern skin flaps. Twenty-seven New Zealand white rabbits were used to determine if prefabricated flaps can be folded 180 degrees around the edge of the rabbits' ears. The survival of these folded prefabricated flaps was compared with the survival of axial pattern flaps sutured into an identically recipient site. In addition, flaps prefabricated in the same manner were sutured onto a straight recipient bed to evaluate the viability of the newly vascularized tissue. The folded prefabricated flaps had reduced survival (56%) compared to equivalent folded axial pattern flaps (85%), P < 0.005. The nonmanipulated prefabricated flaps and axial pattern flaps survived completely.
随着皮瓣预制成为一种更常用的临床手段，有必要研究该技术的局限性。面部重建手术通常需要“定制”皮瓣以满足美学需求。本研究检验并比较了操作薄预制皮瓣与成熟轴型皮瓣的安全性。选用27只新西兰白兔来确定预制皮瓣能否围绕兔耳边缘折叠180度。将这些折叠预制皮瓣的存活情况与缝合到相同受区部位的轴型皮瓣的存活情况进行比较。此外，将以相同方式预制的皮瓣缝合到直线型受区创面上，以评估新血管化组织的活力。与同等折叠的轴型皮瓣（85%）相比，折叠预制皮瓣的存活率降低（56%），P<0.005。未进行操作的预制皮瓣和轴型皮瓣完全存活。
