Tanaka T, Watanabe K, Nakasu S, Handa J
Department of Neurosurgery, Kohka Hospital.
No Shinkei Geka. 1994 Dec;22(12):1141-5.
An extremely rare case of an ectopic pituitary adenoma in the suprasellar region is reported. A 57-year-old man was referred to us in March, 1993, because of bitemporal hemianopsia. Magnetic resonance imaging (MRI) and computed tomography (CT) revealed a well-circumscribed enhancing mass in the suprasellar region. Sagittal tomography of the skull showed normal-sized sella turcica. Endocrinological tests were almost within normal range. The tumor was totally removed by combined right subfrontal and interhemispheric approach. At the time of the operation, we confirmed that the tumor did not continue to the pituitary gland and that the diaphragma sellae was intact. Histological diagnosis of the tumor specimen was pituitary adenoma. Post-operative MRI showed a normal pituitary gland, thus supporting the diagnosis of ectopic pituitary adenoma. To our knowledge, only ten cases of suprasellar ectopic pituitary adenoma have been reported, including our case. Pathogenesis of ectopic pituitary adenoma was briefly discussed.
报告了1例极其罕见的鞍上区异位垂体腺瘤病例。一名57岁男性于1993年3月因双颞侧偏盲转诊至我院。磁共振成像(MRI)和计算机断层扫描(CT)显示鞍上区有一个边界清晰的强化肿块。头颅矢状位断层扫描显示蝶鞍大小正常。内分泌检查几乎在正常范围内。通过右额下入路和经半球间联合入路将肿瘤完全切除。手术时,我们确认肿瘤未延续至垂体,且鞍膈完整。肿瘤标本的组织学诊断为垂体腺瘤。术后MRI显示垂体正常,从而支持异位垂体腺瘤的诊断。据我们所知,包括我们的病例在内,仅报道过10例鞍上异位垂体腺瘤病例。本文简要讨论了异位垂体腺瘤的发病机制。