切断的鱿鱼巨轴突的缩短是不均匀的，且分两个阶段发生。

Shortening of a severed squid giant axon is non-uniform and occurs in two phases.

作者信息

Todora M A, Fishman H M, Krause T L, Bittner G D

机构信息

Department of Physiology and Biophysics, UTMB, Galveston 77555.

出版信息

Neurosci Lett. 1994 Sep 26;179(1-2):57-9. doi: 10.1016/0304-3940(94)90934-2.

DOI:10.1016/0304-3940(94)90934-2

PMID:7845625

Abstract

The shortening of severed squid giant axons (GAs) in vitro was analyzed using video light microscopy. Axonal shortening occurred in two temporal phases along the length of the GA: a rapid initial phase during the first 3.5 min after severance followed by a slower phase lasting at least 30 min. The rate of shortening was greatest near the cut end and declined with distance from the cut end for at least 30 min after transection. Axonal shortening may help pack injury-induced vesicles [3] which facilitate sealing of the cut end [7] and/or retard the entry of various substances.

摘要

利用视频光学显微镜对离体切断的鱿鱼巨轴突（GA）的缩短情况进行了分析。轴突缩短沿GA的长度在两个时间阶段发生：切断后的最初3.5分钟内为快速初始阶段，随后是持续至少30分钟的较慢阶段。缩短速率在切断端附近最大，切断后至少30分钟内，随距切断端距离的增加而下降。轴突缩短可能有助于包装损伤诱导的囊泡[3]，这些囊泡有助于切断端的封闭[7]和/或延缓各种物质的进入。