刺猬（欧洲刺猬）的肌肉提取物可抑制蛇毒的出血活性。

Muscle extract of hedgehog, Erinaceus europaeus, inhibits hemorrhagic activity of snake venoms.

作者信息

Omori-Satoh T, Nagaoka Y, Mebs D

机构信息

Department of Biochemistry and Cell Biology, National Institute of Health, Tokyo, Japan.

出版信息

Toxicon. 1994 Oct;32(10):1279-81. doi: 10.1016/0041-0101(94)90359-x.

DOI:10.1016/0041-0101(94)90359-x

PMID:7846699

Abstract

The antihemorrhagic activity of muscle extract of hedgehog, Erinaceus europaeus, was tested on various snake venoms with hemorrhagic activity. The extract inhibited strongly hemorrhagic activity of venoms from Bitis arietans, Bothrops jararaca and Vipera latastei gaditana, and remarkably that of venoms from Agkistrodon halys blomhoffi, Bitis gabonica rhinoceros, Bitis nasicornis, Bothrops atrox asper, Crotalus horridus horridus and Vipera berus. The antihemorrhagic activity against eight other snake venoms was below the detection level.

摘要

对刺猬（Erinaceus europaeus）肌肉提取物的抗出血活性进行了测试，以检测其对各种具有出血活性的蛇毒的作用。该提取物强烈抑制了鼓腹咝蝰（Bitis arietans）、巴西矛头蝮（Bothrops jararaca）和加迪蝰蛇（Vipera latastei gaditana）蛇毒的出血活性，并显著抑制了日本蝮（Agkistrodon halys blomhoffi）、加蓬咝蝰指名亚种（Bitis gabonica rhinoceros）、角咝蝰（Bitis nasicornis）、亚马逊矛头蝮（Bothrops atrox asper）、东部菱斑响尾蛇（Crotalus horridus horridus）和极北蝰（Vipera berus）蛇毒的出血活性。对其他八种蛇毒的抗出血活性低于检测水平。