Astrup A V, Buemann B, Western P, Toubro S, Raben A, Christensen N J
Den Kgl. Veterinaer- og Landbohøjskole, Forskningsinstitut, for Human Ernaering, Fredericksberg.
Ugeskr Laeger. 1995 Jan 16;157(3):291-4.
A diet rich in fat may be an important precipitating factor of obesity, but studies on this relation have been hampered by the lack of an objective method to assess habitual dietary fat content. We measured 24-h fat oxidation in a respiration chamber in 38 overwight or obese and 35 nonobese women, and used it as an estimate of habitual dietary fat energy (%). After adjustment for confounders, obese women had higher oxidative fat energy than nonobese women [40.2% (37.8-42.6) vs. 36.0% (33.6-38.5), p < 0.02]. Adjusted oxidative fat energy (%) increased with increasing size of fat mass, and this relation suggest that a 10-kg change in fat mass may be caused by a change in dietary fat energy of > or = 1.6%. This objective assessment supports the contention that obese subjects consume a diet with a higher fat content than nonobese individuals, and the high-fat diet may have causal importance for the development and maintenance of obesity.
富含脂肪的饮食可能是肥胖的一个重要诱发因素，但关于这种关系的研究一直受到缺乏评估习惯性饮食脂肪含量的客观方法的阻碍。我们在呼吸室内测量了38名超重或肥胖女性和35名非肥胖女性的24小时脂肪氧化，并将其用作习惯性饮食脂肪能量（%）的估计值。在对混杂因素进行调整后，肥胖女性的氧化脂肪能量高于非肥胖女性[40.2%（37.8 - 42.6）对36.0%（33.6 - 38.5），p < 0.02]。调整后的氧化脂肪能量（%）随着脂肪量的增加而增加，这种关系表明脂肪量每变化10千克可能是由饮食脂肪能量变化≥1.6%引起的。这种客观评估支持了肥胖受试者比非肥胖个体摄入更高脂肪含量饮食的观点，并且高脂肪饮食可能对肥胖的发生和维持具有因果重要性。
