Andresen D, Brüggemann T, Ehlers C
Abt. Kardiologie/Pulmologie, Klinikum Benjamin Franklin, Freie Universität Berlin.
Z Kardiol. 1994;83 Suppl 5:35-9.
Atrial fibrillation is alleged to be one of the most frequently occurring arrhythmia. Many patients with atrial fibrillation are asymptomatic. Others, however, complain of palpitations and paroxysmal atrial tachycardias. And especially in patients with preexisting heart failure, atrial fibrillation can lead to a clear worsening of cardiac output. Not only rheumatic but nonrheumatic atrial fibrillation as well are associated with an increased risk of thromboembolic complications. Arterial hypertension, a history of thromboembolism as well as signs of heart failure are clinical parameters which additionally increase the risk of embolism. On the other hand, this increased risk does not hold true for younger patients with idiopathic atrial fibrillation and is also low in patients with only one additional risk factor. Thus, it would indeed be false to anticoagulate every patient with atrial fibrillation. In each case, a careful individual risk stratification including an extensive history and detailed clinical examination should be performed before deciding on antithrombotic therapy.
房颤据称是最常见的心律失常之一。许多房颤患者没有症状。然而,其他患者会抱怨心悸和阵发性房性心动过速。特别是在已有心力衰竭的患者中,房颤可导致心输出量明显恶化。不仅风湿性房颤,非风湿性房颤也与血栓栓塞并发症风险增加有关。动脉高血压、血栓栓塞病史以及心力衰竭体征是进一步增加栓塞风险的临床参数。另一方面,这种增加的风险在年轻的特发性房颤患者中并不存在,在只有一个额外危险因素的患者中风险也较低。因此,对每一位房颤患者进行抗凝治疗确实是错误的。在每种情况下,在决定抗血栓治疗之前,都应进行仔细的个体风险分层,包括详尽的病史和详细的临床检查。