Marchini C, Romito D, Lucci B, Del Zotto E
Department of Neurology, University Hospital, Udine, Italy.
Acta Neurol Scand. 1994 Sep;90(3):218-21. doi: 10.1111/j.1600-0404.1994.tb02709.x.
We report the case of a 62-year-old man with no past CNS history who for some weeks had had fits of weeping that lasted from 30" to 3', precede by any aura; sensorium was clear; there were no symptoms of any kind after the paroxysm; in the course of them his facial expression was that of weeping with sobbing and tears, but no corresponding affective-emotional content, as reported by the patient, who was able to converse during these episodes. The fits were easily triggered by speaking. EEG during an episode showed a slight flattening of the trace, high voltage sharp waves at 4-6 c/s appeared, especially over the left hemisphere. CT brainscan and cerebral angiogram revealed a large space-occupying lesion of cystic-necrotic appearance with considerable mass effect and characteristics of glioblastoma. Treatment with barbiturates ended the paroxysmal weeping. We consider that these episodes were simple partial epileptic seizure according to the WHO classification of 1981.
我们报告一例62岁男性病例,既往无中枢神经系统病史,数周来反复出现哭泣发作,每次发作持续30秒至3分钟,无任何先兆;发作时意识清楚;发作后无任何症状;发作过程中,其面部表情为哭泣伴抽泣和流泪,但据患者自述,无相应的情感-情绪内容,且患者在发作期间能够交谈。说话很容易诱发发作。发作期间的脑电图显示波形略有平坦,出现4 - 6次/秒的高电压尖波,尤其是在左半球。脑部CT扫描和脑血管造影显示有一个巨大的占位性病变,呈囊性坏死外观,有相当大的占位效应,具有胶质母细胞瘤的特征。使用巴比妥类药物治疗后,阵发性哭泣停止。根据世界卫生组织1981年的分类,我们认为这些发作属于单纯部分性癫痫发作。