Hierholzer J, Hierholzer C, Hierholzer K
Department of Radiology, Universitätsklinikum Rudolf Virchow, Free University of Berlin, Germany.
Am J Nephrol. 1994;14(4-6):467-72. doi: 10.1159/000168767.
Schönlein published few papers, and most of what is known of his achievements in nephrology comes from notes and publications of his students. It seems, however, that he described the combination of rheumatic fever, affection of internal muscular organs, a typical exanthem and oliguria, coining the name purpura rubra to describe this syndrome. Although patients with symptoms of Schönlein's syndrome had been described earlier, Schönlein was the first to describe purpura rheumatica as an entity. Schönlein's greatest contribution was the discovery of the anthropophilic pathogenic fungus Trichophyton schönleinii as the cause of the contagious skin condition favus (honeycomb ringworm). This opened a new field--mycology--and allowed therapy to be aimed specifically at the cause of the disease.
许兰发表的论文很少，人们对他在肾脏病学方面成就的了解大多来自他学生的笔记和出版物。然而，他似乎描述了风湿热、内部肌肉器官病变、典型皮疹和少尿的组合，并创造了“紫癜性红斑”这个名称来描述这种综合征。虽然许兰氏综合征症状的患者在此之前就已被描述，但许兰是第一个将风湿性紫癜作为一个独立病症进行描述的人。许兰最大的贡献是发现了亲人性致病真菌许兰氏毛癣菌是传染性皮肤病黄癣（蜂窝状癣）的病因。这开辟了一个新领域——真菌学——并使治疗能够专门针对疾病的病因。
