Altés A, Martino R, Gari M, Cámara M L, Garín R, Casas J I, Fontcuberta J
Unitat d'Hemostasia i Trombosi, Servei de Cirurgia Cardíaca, Barcelona, Spain.
Ann Thorac Surg. 1995 Feb;59(2):508-9. doi: 10.1016/0003-4975(94)00572-o.
Anticoagulation for cardiopulmonary bypass in the infrequent clinical setting of thrombocytopenia associated with the use of unfractionated heparin is a very serious problem. We describe a case in which a low-molecular-weight heparin (tedelparin) was selected for this purpose based on a platelet aggregation test, permitting adequate anticoagulation during cardiopulmonary bypass for valve replacement. This case report might help establish an adequate anticoagulation protocol when faced with a patient suffering from this condition.
在因使用普通肝素而导致血小板减少这种罕见临床情况下，体外循环时的抗凝是一个非常严重的问题。我们描述了这样一个病例，基于血小板聚集试验选择了低分子量肝素（替地肝素）用于此目的，从而在瓣膜置换的体外循环期间实现了充分抗凝。本病例报告可能有助于在面对患有这种疾病的患者时建立适当的抗凝方案。
