Britt L D, Lambert P, Sharma R, Ladaga L E
Department of General Surgery, Eastern Virginia Medical School, Norfolk.
Arch Surg. 1995 Feb;130(2):221-3. doi: 10.1001/archsurg.1995.01430020111022.
Primary angiosarcoma of the breast is a rare and often misdiagnosed disease. The most common clinical presentation is a painless mass in the affected breast, but the often varied presentation and the high incidence of histologic misdiagnosis make early detection rare. The tumor size and the histologic type correlate with the prognosis. The treatment for angiosarcoma of the breast is early and complete surgical excision of the mass with adequate margins. Axillary dissection is not indicated because the predilection for nodal metastasis is rare. The definitive role of adjuvant therapy remains undetermined. Chemotherapy and radiotherapy may play an important role in survival; however, the data are inconclusive. A high index of suspicion for angiosarcoma is a crucial tool in its proper diagnosis and treatment. It should always be noted that a vascular lesion that is associated with any breast mass is an angiosarcoma until proven otherwise.
原发性乳腺血管肉瘤是一种罕见且常被误诊的疾病。最常见的临床表现是患侧乳房出现无痛性肿块，但由于其表现多样且组织学误诊率高，早期发现较为罕见。肿瘤大小和组织学类型与预后相关。乳腺血管肉瘤的治疗方法是早期完整切除肿块，切缘要足够。不建议进行腋窝清扫，因为淋巴结转移的倾向很少见。辅助治疗的确切作用尚未确定。化疗和放疗可能对生存起重要作用；然而，数据尚无定论。对血管肉瘤保持高度怀疑指数是其正确诊断和治疗的关键工具。应始终牢记，与任何乳腺肿块相关的血管病变在未被证伪之前均为血管肉瘤。
