Muñoz H R, Dagnino J A, Allende M, Bugedo G J, Montes J M, Cherres O G
Departamento de Anestesiología, Hospital Clínico, Universidad Católica de Chile, Santiago.
Reg Anesth. 1993 Nov-Dec;18(6):331-4.
Paresthesias and unblocked segments during continuous epidural anesthesia--sometimes leading to higher doses of local anesthetics--can increase the risk of this technique. A cephalad insertion of the epidural catheter might decrease the incidence of these problems, but this has not been evaluated before in a controlled study.
In a prospective, double-blind, randomized study, we compared the incidence of paresthesias during catheter insertion and the failure rate of continuous epidural anesthesia in two groups of obstetric patients. In group 1 (n = 52), the Tuohy needle bevel was directed cephalad during catheter insertion. In group 2 (n = 53), it was directed caudad. The catheter was introduced 4-5 cm into the epidural space, and bupivacaine 25 mg plus fentanyl 50 micrograms were administered through it.
Twenty percent of the patients in group 1 had paresthesias versus 40% in group 2 (p = 0.0249; 95% confidence interval of the difference 1-40%); intensity of paresthesias was greater in group 2. Pain relief was complete in 75% and 80% of the patients in groups 1 and 2, respectively (NS); three patients in group 1 and one in group 2 had unblocked segments (NS).
Our results support the contention that the catheter should be directed cephalad during insertion for continuous epidural anesthesia.
连续硬膜外麻醉期间的感觉异常和阻滞不全——有时会导致局部麻醉药剂量增加——会增加该技术的风险。硬膜外导管向头端置入可能会降低这些问题的发生率,但此前尚未在对照研究中进行评估。
在一项前瞻性、双盲、随机研究中,我们比较了两组产科患者在导管置入期间感觉异常的发生率以及连续硬膜外麻醉的失败率。第1组(n = 52)在导管置入期间,Tuohy针斜面指向头端。第2组(n = 53),针斜面指向尾端。将导管置入硬膜外间隙4 - 5 cm,并通过导管给予布比卡因25 mg加芬太尼50微克。
第1组20%的患者出现感觉异常,而第2组为40%(p = 0.0249;差异的95%置信区间为1 - 40%);第2组感觉异常的强度更大。第1组和第2组分别有75%和80%的患者疼痛完全缓解(无显著性差异);第1组有3例患者、第2组有1例患者存在阻滞不全(无显著性差异)。
我们的结果支持这样的观点,即连续硬膜外麻醉时,导管置入期间应指向头端。