[糖类抗原Ca 19.9在胰腺癌诊断中有用吗？]
[Is the carbohydrate antigen Ca 19.9 useful in the diagnosis of pancreatic carcinoma?].
作者信息
Santander C, Jiménez I, Martín E, Melón A, Pajares J M
机构信息
Servicio de Medicina Digestiva, Hospital La Princesa, Universidad Autónoma de Madrid.
出版信息
Rev Esp Enferm Dig. 1994 Nov;86(5):819-21.
OBJECTIVE
To determine the sensitivity and specificity of the tumor marker Ca 19.9 in subjects with suspected pancreatic cancer.
MATERIAL AND METHODS
Levels of Ca 19.9 antigen were measured by enzymeimmunoassay during a 3 year period to 72 patients investigated for suspected pancreatic cancer.
RESULTS
A threshold of 100 U/ml resulted in sensitivity of 94.7%, specificity of 39.6%, positive predictive value of 36% and negative predictive value of 95.4%.
CONCLUSION
Levels of Ca 19.9 antigen > 100 U/ml are suggestive of malignancy in patients investigated for suspected pancreatic cancer.
目的
确定肿瘤标志物Ca 19.9在疑似胰腺癌患者中的敏感性和特异性。
材料与方法
在3年期间，采用酶免疫分析法对72例疑似胰腺癌患者检测Ca 19.9抗原水平。
结果
阈值为100 U/ml时，敏感性为94.7%，特异性为39.6%，阳性预测值为36%，阴性预测值为95.4%。
结论
疑似胰腺癌患者中，Ca 19.9抗原水平>100 U/ml提示恶性肿瘤。
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