Okada T, Kawamura T, Tamura T, Toshima R, Sakai O
Second Department of Internal Medicine, Jikei University Medical School, Tokyo.
Intern Med. 1994 Nov;33(11):686-8. doi: 10.2169/internalmedicine.33.686.
Idiopathic Addison's disease developed in a 52-year-old female with a 15-year history of myasthenia gravis. The association of myasthenia gravis with other autoimmune diseases is well known, however an association with Addison's disease is rare. It was speculated that the development of Addison's disease in this patient might have been due to common immunological abnormalities underlying these two diseases. We report this case and briefly discuss the pathogenetic mechanism of this association.
一名患有重症肌无力15年的52岁女性患上了特发性 Addison 病。重症肌无力与其他自身免疫性疾病的关联是众所周知的,然而与Addison病的关联却很罕见。据推测,该患者Addison病的发生可能是由于这两种疾病共同的免疫异常所致。我们报告此病例并简要讨论这种关联的发病机制。