Puttanna Amar, Cunningham Alana Rosaleen, Dainty Philip
Russells Hall Hospital, Dudley, UK.
BMJ Case Rep. 2013 Jul 26;2013:bcr2013010473. doi: 10.1136/bcr-2013-010473.
Addison's disease is a relatively rare endocrine condition resulting from adrenal insufficiency due to various causes. Weight loss is a common feature; however, patients may be seen by a variety of specialists, even requiring acute admission before the diagnosis is made. Addison's disease is commonly associated with other autoimmune diseases. In some cases such as autoimmune polyendocrine syndromes (APS) types 1 and 2, these associations are more commonly found. We present a case of one such patient who presented to the acute medical team having been referred to the gastrointestinal services in the previous year for persistent vomiting and weight loss. On review of history, the cause of vomiting and weight loss was questioned and combined with subsequent biochemical testing a diagnosis of Addison's disease was made. The patient was also noted to have other associated endocrine and autoimmune conditions.
艾迪生病是一种相对罕见的内分泌疾病,由各种原因导致肾上腺功能不全引起。体重减轻是其常见特征;然而,患者可能会被不同专科的医生诊治,甚至在确诊之前需要紧急入院治疗。艾迪生病通常与其他自身免疫性疾病相关。在某些情况下,如1型和2型自身免疫性多内分泌综合征(APS),这种关联更为常见。我们报告一例这样的患者,该患者前一年因持续呕吐和体重减轻被转诊至胃肠科,后被转至急性医疗队。回顾病史时,对呕吐和体重减轻的原因进行了询问,并结合随后的生化检查,确诊为艾迪生病。该患者还被发现患有其他相关的内分泌和自身免疫性疾病。