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艾迪生病及其相关病症。

Addison's disease and its associations.

作者信息

Puttanna Amar, Cunningham Alana Rosaleen, Dainty Philip

机构信息

Russells Hall Hospital, Dudley, UK.

出版信息

BMJ Case Rep. 2013 Jul 26;2013:bcr2013010473. doi: 10.1136/bcr-2013-010473.

DOI:10.1136/bcr-2013-010473
PMID:23893277
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3736622/
Abstract

Addison's disease is a relatively rare endocrine condition resulting from adrenal insufficiency due to various causes. Weight loss is a common feature; however, patients may be seen by a variety of specialists, even requiring acute admission before the diagnosis is made. Addison's disease is commonly associated with other autoimmune diseases. In some cases such as autoimmune polyendocrine syndromes (APS) types 1 and 2, these associations are more commonly found. We present a case of one such patient who presented to the acute medical team having been referred to the gastrointestinal services in the previous year for persistent vomiting and weight loss. On review of history, the cause of vomiting and weight loss was questioned and combined with subsequent biochemical testing a diagnosis of Addison's disease was made. The patient was also noted to have other associated endocrine and autoimmune conditions.

摘要

艾迪生病是一种相对罕见的内分泌疾病,由各种原因导致肾上腺功能不全引起。体重减轻是其常见特征;然而,患者可能会被不同专科的医生诊治,甚至在确诊之前需要紧急入院治疗。艾迪生病通常与其他自身免疫性疾病相关。在某些情况下,如1型和2型自身免疫性多内分泌综合征(APS),这种关联更为常见。我们报告一例这样的患者,该患者前一年因持续呕吐和体重减轻被转诊至胃肠科,后被转至急性医疗队。回顾病史时,对呕吐和体重减轻的原因进行了询问,并结合随后的生化检查,确诊为艾迪生病。该患者还被发现患有其他相关的内分泌和自身免疫性疾病。

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1
Addison's disease and its associations.艾迪生病及其相关病症。
BMJ Case Rep. 2013 Jul 26;2013:bcr2013010473. doi: 10.1136/bcr-2013-010473.
2
Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency.原发性肾上腺功能不全患者的诊断、治疗和随访共识声明。
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3
Gastrointestinal manifestations of Addison's disease.艾迪生病的胃肠道表现。
Am J Gastroenterol. 1989 Oct;84(10):1302-5.
4
[Addison's disease in the framework of poly-glandular autoimmune syndromes: 3 case reports].[多腺体自身免疫综合征框架下的艾迪生病:3例病例报告]
Schweiz Med Wochenschr. 1992 Feb 1;122(5):147-52.
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First presentation of Addison's disease as hyperkalaemia in acute kidney injury.艾迪生病首次表现为急性肾损伤伴高钾血症。
BMJ Case Rep. 2016 May 11;2016:bcr2015213375. doi: 10.1136/bcr-2015-213375.
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Prompt differentiation of Addison's disease from anorexia nervosa during weight loss and vomiting.在体重减轻和呕吐期间迅速鉴别艾迪生病与神经性厌食症。
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Fatal adrenal crisis due to Addison's disease arising in the context of autoimmune polyglandular syndrome type 1.由于 1 型自身免疫性多腺体综合征而导致的艾迪生病引起的致命性肾上腺危象。
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BMJ Case Rep. 2016 Nov 29;2016:bcr2016216302. doi: 10.1136/bcr-2016-216302.
2
Recurrent hypoglycaemia in type-1 diabetes mellitus may unravel the association with Addison's disease: a case report.1型糖尿病患者反复低血糖可能揭示与艾迪生病的关联:一例病例报告
BMC Res Notes. 2014 Sep 12;7:634. doi: 10.1186/1756-0500-7-634.

本文引用的文献

1
Addison disease in adults: diagnosis and management.成人艾迪生病:诊断与治疗。
Am J Med. 2010 May;123(5):409-13. doi: 10.1016/j.amjmed.2009.12.017.
2
Clinical, immunological, and genetic features of autoimmune primary adrenal insufficiency: observations from a Norwegian registry.自身免疫性原发性肾上腺功能不全的临床、免疫和遗传特征:来自挪威登记处的观察结果。
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Addison's disease.艾迪生病
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Thyroxine unmasks Addison's disease.甲状腺素可揭示艾迪生病。
Acta Paediatr. 2004 Dec;93(12):1663-5.
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Autoimmune polyendocrine syndromes.自身免疫性多内分泌综合征
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Update on autoimmune polyendocrine syndromes (APS).自身免疫性多内分泌综合征(APS)的最新进展。
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Clinical review 93: Autoimmune polyglandular syndrome type 1.临床综述93:1型自身免疫性多内分泌腺综合征
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