Buhl M, Liesenhoff O, Kampik A
Augenklinik, Universität München.
Ophthalmologe. 1994 Dec;91(6):741-4.
There is no consensus in the literature on the etiology and therapy of central serous retinopathy. We conducted a retrospective study to find out whether patients treated with argon laser coagulation (ALK) experienced long-term visual acuity improvement. We were also concerned to find whether choroidal perfusion was involved in the etiology.
In all, 28 patients (4 women/24 men) with RCS confirmed by angiography were analyzed. All patients were followed up from 1988 to 1992. Patients with chronic recurrent RCS were not considered. Angiography was performed to examine the type and localization of the leakage and also the choroidal perfusion. Patients who were treated with ALK were compared with patients who were not.
Only 9 patients were treated with carefully directed ALK. Their mean visual acuity was 0.5 (STD 0.09) before therapy. After treatment the mean visual acuity was improved to an average of 0.8 (0.23). The follow-up time was up to 56 weeks. The patients without ALK had an initial visual acuity of 0.6 (0.21) which improved to 0.8 (0.22) during an observation period of 60 weeks. By the end of the study the visual acuity was the same in both groups. In 46% of all patients delayed choroidal perfusion was seen on angiography.
There was no difference in visual acuity between patients treated with and without ALK. The angiographic examinations suggest general changes in choroidal perfusion in patients with RCS.
关于中心性浆液性视网膜病变的病因和治疗,文献中尚无共识。我们进行了一项回顾性研究,以确定接受氩激光凝固术(ALK)治疗的患者视力是否能得到长期改善。我们还关注脉络膜灌注是否参与了其病因。
共分析了28例经血管造影确诊为RCS的患者(4名女性/24名男性)。所有患者于1988年至1992年进行随访。慢性复发性RCS患者未纳入考虑。进行血管造影以检查渗漏的类型和部位以及脉络膜灌注情况。将接受ALK治疗的患者与未接受治疗的患者进行比较。
仅9例患者接受了精确导向的ALK治疗。治疗前他们的平均视力为0.5(标准差0.09)。治疗后平均视力提高到0.8(0.23)。随访时间长达56周。未接受ALK治疗的患者初始视力为0.6(0.21),在60周的观察期内提高到0.8(0.22)。到研究结束时,两组的视力相同。在所有患者中,46%的患者在血管造影中可见脉络膜灌注延迟。
接受ALK治疗和未接受治疗的患者在视力上没有差异。血管造影检查提示RCS患者脉络膜灌注存在普遍变化。