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细菌和噬菌体重组系统以及DNA复制在紫外线照射的噬菌体λ遗传重组中的作用。

Role of the bacterial and phage recombination systems and of DNA replication in genetic recombination of UV-irradiated phage Lambda.

作者信息

Blanco M, Armengod M E

出版信息

Mol Gen Genet. 1976 Jul 5;146(1):51-4. doi: 10.1007/BF00267982.

DOI:10.1007/BF00267982
PMID:785209
Abstract

In this paper are studied in E. coli K12 the influence of the bacterial Rec and phage mu Red recombination systems on the rescue of the O plus gene from the prophage by a superinfecting O minus phage, UV irradiated or not. In the absence of UV irradiation the Red system produces more recombinants than does the Rec system, and its action requires DNA replication. The presence of UV lesions in the mu DNA facilitates the action of the Rec system, which is more efficient in this instance than the Red system and can act in the absence of DNA replication. In all cases, there is a cooperation between the two generalized recombination systems.

摘要

本文研究了大肠杆菌K12中细菌Rec和噬菌体μRed重组系统对超感染的O-噬菌体(无论是否经紫外线照射)从原噬菌体中拯救O+基因的影响。在没有紫外线照射的情况下,Red系统比Rec系统产生更多的重组体,并且其作用需要DNA复制。μDNA中紫外线损伤的存在促进了Rec系统的作用,在这种情况下Rec系统比Red系统更有效,并且可以在没有DNA复制的情况下发挥作用。在所有情况下,这两个广义重组系统之间都存在协同作用。

相似文献

1
Role of the bacterial and phage recombination systems and of DNA replication in genetic recombination of UV-irradiated phage Lambda.细菌和噬菌体重组系统以及DNA复制在紫外线照射的噬菌体λ遗传重组中的作用。
Mol Gen Genet. 1976 Jul 5;146(1):51-4. doi: 10.1007/BF00267982.
2
Genetic exchanges caused by ultraviolet photoproducts in phage lambda DNA molecules: the role of DNA replication.噬菌体λ DNA 分子中紫外线光产物引起的基因交换:DNA 复制的作用。
Mol Gen Genet. 1976 Jul 23;146(2):107-15. doi: 10.1007/BF00268079.
3
Repair mechanisms involved in the recovery of phage lambda from ultraviolet damage.参与噬菌体λ从紫外线损伤中恢复的修复机制。
An Acad Bras Cienc. 1973;45 SUPPL:193-201.
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Behavior of lambda bacteriophage in a recombination deficienct strain of Escherichia coli.λ噬菌体在大肠杆菌重组缺陷菌株中的行为
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[Degradation by the host cell of DNA of lambda bacteriophage irradiated by ultraviolet rays].[宿主细胞对紫外线照射的λ噬菌体DNA的降解作用]
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引用本文的文献

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Homologous Recombination-Experimental Systems, Analysis, and Significance.同源重组——实验系统、分析及意义
EcoSal Plus. 2011 Dec;4(2). doi: 10.1128/ecosalplus.7.2.6.
2
Role of the recF gene of Escherichia coli K-12 in lambda recombination.大肠杆菌K-12的recF基因在λ噬菌体重组中的作用。
Mol Gen Genet. 1981;181(4):497-504. doi: 10.1007/BF00428742.

本文引用的文献

1
[Genetic study of a temperate bacteriophage of Escherichia coli. III. Effect of ultraviolet rays on genetic recombination].[大肠杆菌一种温和噬菌体的遗传学研究。III. 紫外线对基因重组的影响]
Ann Inst Pasteur (Paris). 1955 Jun;88(6):724-49.
2
Recombination in bacteriophage lambda. I. Mutants deficient in general recombination.噬菌体λ中的重组。I. 一般重组缺陷型突变体
J Mol Biol. 1968 Jul 14;34(2):261-71. doi: 10.1016/0022-2836(68)90251-9.
3
Control of development in temperate bacteriophages. 3. Which prophage genes are and which are not trans-activable in the presence of immunity?
温和噬菌体发育的调控。3. 在存在免疫性的情况下,哪些原噬菌体基因是可反式激活的,哪些不是?
J Mol Biol. 1970 Apr 28;49(2):393-404. doi: 10.1016/0022-2836(70)90252-4.
4
Roles of parental and progeny DNA in 2 mechanisms of phage S13 recombination.
Nat New Biol. 1971 Mar 3;230(1):23-5. doi: 10.1038/newbio230023a0.
5
The role of recombination in transfection of B. subtilis.重组在枯草芽孢杆菌转染中的作用。
Mol Gen Genet. 1971;113(2):174-90. doi: 10.1007/BF00333191.
6
Replication of bacteriophage DNA. I. Replication of DNA of lambda phage defective in early functions.噬菌体DNA的复制。I. 早期功能有缺陷的λ噬菌体DNA的复制
J Mol Biol. 1968 Dec 14;38(2):217-25. doi: 10.1016/0022-2836(68)90407-5.
7
Regulation of lambda exonuclease synthesis: role of the N gene product and lambda repressor.λ外切核酸酶合成的调控:N基因产物和λ阻遏物的作用
J Mol Biol. 1970 Apr 28;49(2):515-9. doi: 10.1016/0022-2836(70)90261-5.
8
UV-induced enhancement of recombination among lambda bacteriophages in UV-sensitive host bacteria.紫外线诱导的紫外线敏感宿主细菌中λ噬菌体间重组增强。
Mol Gen Genet. 1967;100(2):166-77. doi: 10.1007/BF00333603.
9
On the physical structure of lambda recombinant DNA.关于λ重组DNA的物理结构
Mol Gen Genet. 1973 May 28;122(4):353-66. doi: 10.1007/BF00269436.
10
Repair mechanisms involved in prophage reactivation and UV reactivation of UV-irradiated phage lambda.与紫外线照射的噬菌体λ的原噬菌体复活和紫外线复活相关的修复机制。
Mutat Res. 1973 Mar;17(3):293-305. doi: 10.1016/0027-5107(73)90001-8.