Becker C R, Schad L R, Lorenz W J
Forschungsschwerpunkt Radiologische Diagnostik und Therapie, Deutsches Krebsforschungszentrum (dkfz), Heidelberg, Germany.
Magn Reson Imaging. 1994;12(8):1167-74. doi: 10.1016/0730-725x(94)90082-3.
A new method for the ultrafast generation of diffusion-weighted images is reported. The technique combines a quick echo split NMR imaging sequence with the principle of Stejskal and Tanner. It allows to determine the diffusion constant with nearly the same accuracy as the conventional spin-echo technique, requiring only a fraction of the time. The determined values for water doped with 1 g Cu(NO3)2 per liter of H2O and pure acetone were Dwater = (1.95 +/- 0.02) x 10(-9) m2/s and Dacetone = (4.05 +/- 0.02) x 10(-9) m2/s at 18.5 degrees C. They are in good agreement both with literature and our own reference measurements using a diffusion-weighted spin-echo sequence. In addition, the temperature dependence of Dwater was measured in the range of 18.5-45.9 degrees C and a good correspondence with reported data was found.
报道了一种用于超快生成扩散加权图像的新方法。该技术将快速回波分裂核磁共振成像序列与斯泰卡尔和坦纳原理相结合。它能够以与传统自旋回波技术几乎相同的精度测定扩散常数，而所需时间仅为其一小部分。在18.5℃下，每升H₂O中掺杂1 g Cu(NO₃)₂的水以及纯丙酮的测定值分别为D水 = (1.95 ± 0.02)×10⁻⁹ m²/s和D丙酮 = (4.05 ± 0.02)×10⁻⁹ m²/s。这些值与文献以及我们自己使用扩散加权自旋回波序列的参考测量结果都非常吻合。此外，在18.5 - 45.9℃范围内测量了D水的温度依赖性，发现与报道数据有良好的对应关系。
