Harada M, Tanouchi M, Miyoshi H, Nishitani H, Kannuki S
Department of Radiology, School of Medicine, University of Tokushima, Japan.
Magn Reson Imaging. 1994;12(8):1269-74. doi: 10.1016/0730-725x(94)90092-6.
We encountered a case of brain abscess that was difficult to differentiate from glioblastoma. Localized 1H-MRS was found to be useful for obtaining information on the biochemical status of brain abscess. The peak of lipid and high residual peak of NAA (N-acetyl-aspartate) were observed in the cystic lesion of the brain abscess by 1H-MRS. The NAA/Cho (Choline-containing compounds) ratio in brain parenchyma showing an edematous lesion before therapy gradually increased with the relief of inflammation.
我们遇到一例难以与胶质母细胞瘤相鉴别的脑脓肿病例。发现局部1H - MRS有助于获取脑脓肿生化状态的信息。通过1H - MRS在脑脓肿的囊性病变中观察到脂质峰和较高的NAA（N - 乙酰天门冬氨酸）残留峰。治疗前显示有水肿性病变的脑实质中NAA/Cho（含胆碱化合物）比值随着炎症缓解而逐渐升高。
