Reyes-Mugica M, Alvarez-Franco M, Bauer B S, Vicari F A
Department of Pathology, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois.
Pediatr Pathol. 1994 Nov-Dec;14(6):1029-41. doi: 10.3109/15513819409037699.
Nevomelanocytic lesions in children represent a wide spectrum of proliferative neurocristopathies, ranging from the common small and benign congenital nevi to the garment-type congenital lesions. Included in this spectrum are some rare entities like neurocutaneous melanocytosis, malignant melanoma simulants, and special variants of congenital pigmented nevi. Here, we analyze some tissue culture characteristics of nevomelanocytic cells from giant and small congenital nevi, neurocutaneous melanocytosis, and a rare variant of nevus named "bulky nevocytoma." Correlations with their histological, immunohistochemical, and ultrastructural features are addressed.
儿童的痣黑素细胞性病变代表了一系列增殖性神经嵴病变，范围从常见的小而良性的先天性痣到皮样先天性病变。这一病变谱系中包括一些罕见的实体，如神经皮肤黑素沉着症、恶性黑色素瘤模拟物以及先天性色素痣的特殊变体。在此，我们分析了来自巨大和小先天性痣、神经皮肤黑素沉着症以及一种名为“巨大痣细胞瘤”的罕见痣变体的痣黑素细胞的一些组织培养特征。探讨了它们与组织学、免疫组织化学和超微结构特征的相关性。
