Peinado Peinado R, Arenal Maíz A, Almendral Garrote J, Pérez Villacastín J, Merino Llorens J L, Martínez-Alday J D, Pastor Fuentes A, Medina Moreno O, Valero Parra R, Delcán Domínguez J L
Laboratorio de Electrofisiología-Clínica Cardíaca, Hospital General Gregorio Marañón, Madrid.
Rev Esp Cardiol. 1994 Dec;47(12):803-10.
It has been suggested that the efficacy of radiofrequency ablation of idiopathic ventricular tachycardia (VT) is dependent on the site of VT origin, with the efficacy being greater for VTs originating from right ventricle. The electrophysiologic characteristic and the results of radiofrequency catheter ablation of ventricular tachycardia in patients without structural heart disease are reported. Special emphasis was focused to the differences observed in the pace and activating mapping between VTs originating in the right ventricle and those originating from the left ventricle and its possible implications for radiofrequency efficacy.
14 consecutive patients with idiopathic VT (7 women and 7 men, mean age 35 +/- 16 years), 8 originating in the right ventricle (RV) and 6 in the left ventricle (LTV), underwent catheter ablation using radiofrequency energy. The observation of entrainment with fusion in all LV VT suggested that the electrophysiologic mechanism was a reentry, meanwhile the RV VT were due to focal non-reentrant mechanisms. Sites for radiofrequency energy delivery were selected on the basis of pace and activation mapping in all patients less in two patients with incessant VT in whom only activation mapping was performed. 14 VT were mapped. The activation mapping demonstrated isolated presystolic electrograms in the point of origin in all VT arising from the LV. However in RV tachycardias there was continuous activity between presystolic and systolic electrograms, although the prematurity of these electrograms was similar (31 +/- 16 ms vs 33 +/- 9 ms; p = 0.77). Radiofrequency was successful in eliminating 93% of TV (100% RV TV vs 83% LV TV; p = 0.23). No complications were observed.
The results of this study suggest that radiofrequency ablation is highly successful either in right and left ventricles idiopathic tachycardias when pace and activation mapping are used complementary.
有人提出,特发性室性心动过速(VT)的射频消融疗效取决于VT起源部位,起源于右心室的VT疗效更佳。本文报道了无结构性心脏病患者室性心动过速的电生理特征及射频导管消融结果。特别强调了起源于右心室和左心室的VT在起搏和激动标测中观察到的差异及其对射频疗效的可能影响。
连续14例特发性VT患者(7例女性,7例男性,平均年龄35±16岁),8例起源于右心室(RV),6例起源于左心室(LVT),接受了射频能量导管消融。所有左心室VT的融合带拖带观察提示电生理机制为折返,而右心室VT则是由于局灶性非折返机制。在所有患者中,根据起搏和激动标测选择射频能量释放部位,2例无休止性VT患者仅进行了激动标测。共对14次VT进行了标测。激动标测显示,所有起源于左心室的VT在起源点均有孤立的收缩前期电图。然而,在右心室心动过速中,收缩前期和收缩期电图之间存在连续活动,尽管这些电图的提前程度相似(31±16 ms对33±9 ms;p = 0.77)。射频成功消除了93%的VT(右心室VT为100%,左心室VT为83%;p = 0.23)。未观察到并发症。
本研究结果提示,当起搏和激动标测互补使用时,射频消融在右心室和左心室特发性心动过速中均非常成功。