Smith E, Orholm M K
Department of Epidemiology, Statens Seruminstitut, Copenhagen, Denmark.
Scand J Infect Dis. 1994;26(5):517-22. doi: 10.3109/00365549409011809.
The frequency of PCP among adult Danish AIDS patients notified in 1988-93 was higher among patients tested HIV-positive less than 4 months prior to AIDS than among those known to be positive for > 1 year. Among the latter, the proportion with PCP decreased significantly over the period, from 45.3% in 1988 to 22.0% in 1993, while no such trend was found among patients tested positive for HIV less than 4 months before AIDS was diagnosed. The incidence of PCP as an AIDS-defining disease has decreased, most likely due to the use of PCP prophylaxis.
1988 - 1993年报告的成年丹麦艾滋病患者中,艾滋病确诊前不到4个月检测出HIV阳性的患者发生肺孢子菌肺炎(PCP)的频率高于已知HIV阳性超过1年的患者。在后者中,PCP患者比例在此期间显著下降,从1988年的45.3%降至1993年的22.0%,而在艾滋病确诊前不到4个月检测出HIV阳性的患者中未发现这种趋势。作为艾滋病界定疾病的PCP发病率有所下降,很可能是由于采用了PCP预防措施。