Horrevorts A M, Huysmans F T, Koopman R J, Meis J F
Department of Medical Microbiology, University Hospital Nijmegen, The Netherlands.
Scand J Infect Dis. 1994;26(5):623-6. doi: 10.3109/00365549409011823.
Two renal transplant recipients with cellulitis due to Cryptococcus neoformans are described. The patients were treated empirically for a presumed bacterial erysipelas, but without response. Examination of skin biopsies revealed C. neoformans as the causative organism. In both patients the cellulitis was the presenting clinical manifestation of disseminated cryptococcosis. Therapy with antifungal agents was successful. Disseminated cryptococcal disease occurs mainly in immunocompromised patients. When left untreated, it nearly always has a fatal course. Early diagnosis and appropriate therapy are therefore essential.
本文描述了两名因新型隐球菌引起蜂窝织炎的肾移植受者。这两名患者最初按疑似细菌性丹毒进行经验性治疗，但未见疗效。皮肤活检显示新型隐球菌为病原体。两名患者的蜂窝织炎均为播散性隐球菌病的首发临床表现。抗真菌药物治疗取得成功。播散性隐球菌病主要发生在免疫功能低下的患者中。若不治疗，几乎总会导致致命后果。因此，早期诊断和适当治疗至关重要。
