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[皮肤移植在静脉性(血栓形成后)静脉曲张溃疡治疗方案中的作用]

[The role of skin transplantation in the treatment plan of venous (post-thrombotic) varicose ulcer].

作者信息

Sebastian G

机构信息

Klinik und Poliklinik für Dermatologie, Universitätsklinikums Carl Gustav Carus, Technischen Universität Dresden, Deutschland.

出版信息

Wien Med Wochenschr. 1994;144(10-11):269-72.

PMID:7856205
Abstract

Under both inpatient and outpatient conditions several skin grafting techniques (eg. split-skin meshgraft, postage stampgrafts) can be useful in treating already phlebosurgically operated venous ulcers. 82 already phlebosurgically longterm treated venous ulcers were skin grafted under clinical conditions in the time from 1983 to 1992. Various characteristics of this patient-group (eg. age, sex, duration of disease, localization and size of venous ulcer) were put retrospectively into comparison with those of 72 patients suffering from venous ulcers treated exclusively in a conservative manner. Patients of the skin grafted group - aged mostly 55 to 65 years - suffered longer from chronic venous ulcers, of which 15 were circulatory. The time interval between clinical admission and skin grafting (16th to 28th day), the index of healing dependent indicator for the dermato-surgical intervention, as well as short and long term results, were investigated. In contrast to favourable short term results (39 patients with complete, 17 with > 50% settlement of skin graft) long term results were rather disappointing. 27 of 39 operated patients with initially successfully treated venous ulcers answered a questionnaire in which, as a result, only 15 did not suffer a relapse one to nine years after the dermatosurgical intervention. Despite of these results, simple techniques of skin grafting will still be in future of great value.

摘要

在住院和门诊条件下,几种皮肤移植技术(如分层皮片网状移植、邮票状移植)可用于治疗已经接受静脉外科手术的静脉性溃疡。1983年至1992年期间,在临床条件下对82例已经接受长期静脉外科治疗的静脉性溃疡患者进行了皮肤移植。将该患者组的各种特征(如年龄、性别、病程、静脉性溃疡的部位和大小)与72例仅接受保守治疗的静脉性溃疡患者的特征进行了回顾性比较。皮肤移植组的患者大多年龄在55至65岁之间,患有慢性静脉性溃疡的时间更长,其中15例有循环问题。研究了临床入院与皮肤移植之间的时间间隔(第16至28天)、皮肤外科手术愈合相关指标以及短期和长期结果。与良好的短期结果(39例完全愈合,17例皮肤移植愈合率>50%)相比,长期结果相当令人失望。39例最初成功治疗静脉性溃疡的手术患者中有27例回答了一份问卷,结果显示,在皮肤外科手术后1至9年,只有15例没有复发。尽管有这些结果,但简单的皮肤移植技术在未来仍将具有重要价值。

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