Schmidt A
Kinderchirurgische Klinik, Universität München.
Eur J Pediatr Surg. 1994 Oct;4(5):310-4. doi: 10.1055/s-2008-1066123.
In a retrospective study the manometrical findings of 27 patients with histochemically confirmed isolated NID were compared with the findings of 14 patients with habitual constipation. In a second group NID or other neuronal disorders of the distal colon were excluded by histology/histochemistry. Significant differences were found only for the amplitude and frequency of anorectal fluctuations and for presence or absence of rectoanal inhibitory reflexes (RAIR). All other investigated parameters were not significant. In conclusion a reliable diagnosis of isolated NID is only possibly by combined use of anorectal manometry and histochemistry. Nevertheless anorectal manometry remains an important tool for screening in constipative disorders and should be performed prior to other investigations i.e. radiology or biopsy.
在一项回顾性研究中，将27例经组织化学确诊为孤立性先天性巨结肠（NID）患者的测压结果与14例习惯性便秘患者的结果进行了比较。在第二组中，通过组织学/组织化学排除了先天性巨结肠或远端结肠的其他神经元疾病。仅在肛门直肠波动的幅度和频率以及是否存在直肠肛门抑制反射（RAIR）方面发现了显著差异。所有其他研究参数均无统计学意义。总之，仅通过联合使用肛门直肠测压法和组织化学才能可靠地诊断孤立性先天性巨结肠。然而，肛门直肠测压法仍然是便秘性疾病筛查的重要工具，应在其他检查（如放射学检查或活检）之前进行。
