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偏差溶解:补体溶解活性向未致敏细胞的转移II. 菊粉和抗原抗体复合物产生活性

Deviated lysis: Transfer of complement lytic activity to unsensitized cells II. Generation of the activity by inulin and by antigen antibody complexes.

作者信息

Rother U, Hänsch G, Rother K

出版信息

Z Immunitatsforsch Immunobiol. 1976 Aug;151(1):442-54.

PMID:785847
Abstract

Deviated lysis (d.l.) activity, i.e. lysis of unsensitized cells by lytic C activity, was generated via the classical pathway of Cactivation (ag ab complexes) and via the alternative pathway (inulin). The activity was observed on the surface of the activating particles and in the fluid phase. The activity was relatively stable at 32 degrees C. Its generation involved the C components C6 through C9 and possibly also C5.

摘要

偏离性溶解(d.l.)活性,即通过溶细胞补体(C)活性对未致敏细胞的溶解作用,可通过补体激活的经典途径(抗原-抗体复合物)以及替代途径(菊粉)产生。该活性在激活颗粒表面和液相中均可观察到。在32摄氏度时,该活性相对稳定。其产生涉及补体成分C6至C9,可能还涉及C5。

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