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中性粒细胞减少患者细菌感染的经验性治疗。

Empirical therapy for bacterial infections in neutropenic patients.

作者信息

Klastersky J

机构信息

Service de Médecine, Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, Belgium.

出版信息

Support Care Cancer. 1994 Nov;2(6):347-54. doi: 10.1007/BF00344047.

DOI:10.1007/BF00344047
PMID:7858926
Abstract

Infection in neutropenic patients remains a continuing challenge as the modalities of cancer treatment evolve and new pathogens appear. Although the concept of empirical therapy remains valid, there is a need for adaptation of our therapeutic approaches to new clinical and microbiological evidence.

摘要

随着癌症治疗方式的演变以及新病原体的出现,中性粒细胞减少患者的感染仍然是一个持续存在的挑战。尽管经验性治疗的概念仍然有效,但我们需要根据新的临床和微生物学证据调整治疗方法。

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1
Empirical therapy for bacterial infections in neutropenic patients.中性粒细胞减少患者细菌感染的经验性治疗。
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2
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引用本文的文献

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Ceftriaxone/Amikacin vs Ceftazidime/Amikacin as Empirical Therapy for Fever in Patients with Haematological Malignancy and Severe Granulocytopenia: Clinical and Economic Outcomes.头孢曲松/阿米卡星与头孢他啶/阿米卡星治疗血液恶性肿瘤伴严重粒细胞减少发热患者的经验性治疗:临床和经济结局。
Clin Drug Investig. 1998;15(5):425-33. doi: 10.2165/00044011-199815050-00007.
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Clinical and economic considerations of empirical antibacterial therapy of febrile neutropenia in cancer.癌症患者发热性中性粒细胞减少症经验性抗菌治疗的临床与经济考量
Pharmacoeconomics. 1999 Oct;16(4):343-53. doi: 10.2165/00019053-199916040-00003.
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Infectious complications of combination anticancer chemotherapy for urogenital cancers.

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Fever of unexplained origin: report on 100 cases.不明原因发热:100例报告。
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Acyclovir prophylaxis of herpes-simplex-virus infections.阿昔洛韦对单纯疱疹病毒感染的预防
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7
Empiric therapy with carbenicillin and gentamicin for febrile patients with cancer and granulocytopenia.对患有癌症和粒细胞减少症的发热患者采用羧苄青霉素和庆大霉素进行经验性治疗。
N Engl J Med. 1971 May 13;284(19):1061-5. doi: 10.1056/NEJM197105132841904.
8
Clinical significance of in vitro synergism between antibiotics in gram-negative infections.革兰氏阴性菌感染中抗生素体外协同作用的临床意义。
Antimicrob Agents Chemother. 1972 Dec;2(6):470-5. doi: 10.1128/AAC.2.6.470.
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Aztreonam therapy in neutropenic patients with cancer.
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10
Empiric use of vancomycin during prolonged treatment-induced granulocytopenia. Randomized, double-blind, placebo-controlled clinical trial in patients with acute leukemia.在长期治疗引起的粒细胞减少症期间经验性使用万古霉素。针对急性白血病患者的随机、双盲、安慰剂对照临床试验。
Am J Med. 1986 Aug;81(2):237-42. doi: 10.1016/0002-9343(86)90257-3.