慢性肾病患者使用氨甲环酸剂量的特殊注意事项。
Special considerations with regard to the dosage of tranexamic acid in patients with chronic renal diseases.
作者信息
Andersson L, Eriksson O, Hedlund P O, Kjellman H, Lindqvist B
出版信息
Urol Res. 1978;6(2):83-8. doi: 10.1007/BF00255578.
PMID:664136
Abstract
Tranexamic acid is a potent antifibrinolytic drug frequently used in the treatment of haematuria and a number of other haemorrhagic conditions. Since it is eliminated mainly in the urine, the drug accumulates in patients with uraemia. The excretion of tranexamic acid in patients with renal failure has been investigated and dosage recommendations are given for tranexamic acid therapy in cases of renal failure.
摘要
氨甲环酸是一种强效抗纤溶药物，常用于治疗血尿及其他多种出血性病症。由于它主要经尿液排泄，因此在尿毒症患者体内会蓄积。已对肾衰竭患者氨甲环酸的排泄情况进行了研究，并给出了肾衰竭病例中氨甲环酸治疗的剂量建议。
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