Harjai K J, Kamble M S, Ashar V J, Anklesaria P S, Ratnam K L, Abraham P
Department of Gastroenterology, King Edward VII Memorial Hospital, Bombay, India.
Cleve Clin J Med. 1995 Jan-Feb;62(1):62-7. doi: 10.3949/ccjm.62.1.62.
Other investigators have found the serum-ascites albumin concentration gradient to be 1.1 g/dL or greater in the presence of portal hypertension and less than that in its absence.
To determine if any correlation exists between the serum-ascites albumin concentration gradient (which reflects the net serum oncotic pressure) and the portal venous pressure.
The study group comprised 15 patients who had alcoholic cirrhosis. The portal venous pressure was calculated as the difference between the measured hepatic venous wedge and inferior vena cava pressures and was expressed as the hepatic venous pressure gradient.
All patients had portal hypertension; the mean hepatic venous pressure gradient was 14.81 +/- 6.91 (SD) mm Hg. Fourteen of the 15 patients had a serum-ascites albumin concentration gradient of at least 1.1 g/dL; the mean value was 2.168 +/- .709 g/dL. No correlation was found between these variables (r = .0459, P > .05).
Although the serum-ascites albumin concentration gradient is a sensitive indicator of portal hypertension in patients with alcoholic cirrhosis, it does not reflect the portal venous pressure.
其他研究人员发现，在存在门静脉高压的情况下，血清-腹水白蛋白浓度梯度为1.1g/dL或更高，而在不存在门静脉高压的情况下则低于该值。
确定血清-腹水白蛋白浓度梯度（反映血清净胶体渗透压）与门静脉压力之间是否存在任何相关性。
研究组包括15例酒精性肝硬化患者。门静脉压力通过测量的肝静脉楔压与下腔静脉压力之差计算得出，并表示为肝静脉压力梯度。
所有患者均有门静脉高压；平均肝静脉压力梯度为14.81±6.91（标准差）mmHg。15例患者中有14例血清-腹水白蛋白浓度梯度至少为1.1g/dL；平均值为2.168±0.709g/dL。这些变量之间未发现相关性（r = 0.0459，P>0.05）。
尽管血清-腹水白蛋白浓度梯度是酒精性肝硬化患者门静脉高压的敏感指标，但它并不能反映门静脉压力。
