Kuzuya T, Akanuma Y, Akazawa Y, Uehata T
Jichi Medical School, Tochigi-ken, Japan.
Diabetes Res Clin Pract. 1994 Oct;24 Suppl:S159-64. doi: 10.1016/0168-8227(94)90244-5.
In November 1990, we carried out a survey of chronic complications of diabetes in more than 2000 diabetic patients who were seen on one day in 35 medical institutions including university hospitals, other hospitals and small clinics. More than 60% were aged 55-74 years. About 7% of patients had IDDM. Hypertension was present in 38.5%. Proteinuria was positive in 20% and 1% of patients were on dialysis therapy. 28% had visual disturbance and 2.9% had blindness in one or both eyes. Retinopathy was observed in 38% and proliferative retinopathy in 10%. The prevalences of myocardial infarction, angina pectoris, cerebral infarction and foot ulcer and gangrene were 2.1%, 4.7%, 5.7% and 2%, respectively, including the histories of these complications. Amputation of lower extremities was seen in only 0.6%. Microangiopathies were generally more frequent and more severe in IDDM than NIDDM. The prevalence of microangiopathy was as common as, but macroangiopathy seems less frequent than, the figures given in 'Diabetes in America'.
1990年11月，我们对2000多名糖尿病患者的糖尿病慢性并发症进行了调查，这些患者于同一天在包括大学医院、其他医院和小诊所在内的35家医疗机构就诊。超过60%的患者年龄在55 - 74岁之间。约7%的患者患有胰岛素依赖型糖尿病（IDDM）。38.5%的患者患有高血压。20%的患者蛋白尿呈阳性，1%的患者接受透析治疗。28%的患者有视力障碍，2.9%的患者一只或两只眼睛失明。38%的患者观察到视网膜病变，10%的患者有增殖性视网膜病变。包括这些并发症病史在内，心肌梗死、心绞痛、脑梗死以及足部溃疡和坏疽的患病率分别为2.1%、4.7%、5.7%和2%。下肢截肢仅见于0.6%的患者。微血管病变在IDDM中通常比非胰岛素依赖型糖尿病（NIDDM）更频繁、更严重。微血管病变的患病率与《美国糖尿病》中的数据相当，但大血管病变似乎比其数据更为少见。
