Gheysens B, Baste J C, Midy D, Pheline P, Alessandrin J F, Parrens M, De Mascarel A
Service de Chirurgie Générale et Vasculaire, Hôpital St André, Bordeaux.
J Chir (Paris). 1994 Nov;131(11):492-5.
A retroperitoneal localization of Castleman's disease was characterized by angiolymphoid hyperplasia. This rare disease (58 cases of abdominal localization reported to date) raises a question of nosology. The clinical features are not specific. Localized forms in young patients involve deep lymph nodes and have a good prognosis after complete surgical exeresis. Inversely, the clinical picture is much more aggressive in multiple localizations involving preferentially superficial nodes with associated plasmocyte proliferation. The prognosis is mediocre in these forms. Although transition stages have been described due to the lack of any known aetiology, the question of nosology remains open: should the different forms be separated or identified simply as two pathological forms?
卡斯特leman病的腹膜后定位以血管淋巴样增生为特征。这种罕见疾病(迄今报道有58例腹部定位病例)引发了分类学问题。其临床特征并不特异。年轻患者的局限性形式累及深部淋巴结,完整手术切除后预后良好。相反,多部位形式的临床表现更具侵袭性,优先累及浅表淋巴结并伴有浆细胞增生。这些形式的预后一般。尽管由于缺乏任何已知病因已描述了过渡阶段,但分类学问题仍然悬而未决:不同形式应分开还是仅视为两种病理形式?