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Response to specific anti-oestrogen (ICI182780) in tamoxifen-resistant breast cancer.

作者信息

Dowsett M, Johnston S R, Iveson T J, Smith I E

出版信息

Lancet. 1995 Feb 25;345(8948):525. doi: 10.1016/s0140-6736(95)90624-x.

DOI:10.1016/s0140-6736(95)90624-x
PMID:7861903
Abstract
摘要

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Response to specific anti-oestrogen (ICI182780) in tamoxifen-resistant breast cancer.他莫昔芬耐药乳腺癌对特异性抗雌激素(ICI182780)的反应。
Lancet. 1995 Feb 25;345(8948):525. doi: 10.1016/s0140-6736(95)90624-x.
2
Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancer.他莫昔芬耐药乳腺癌对特定抗雌激素(ICI 182780)的反应。
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Effects of short-term antiestrogen treatment of primary breast cancer on estrogen receptor mRNA and protein expression and on estrogen-regulated genes.原发性乳腺癌短期抗雌激素治疗对雌激素受体mRNA和蛋白质表达以及雌激素调节基因的影响。
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Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancer.他莫昔芬耐药性乳腺癌对特定抗雌激素(ICI 182780)的反应
Lancet. 1995 Jan 7;345(8941):29-30. doi: 10.1016/s0140-6736(95)91156-1.
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Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action.氟维司群:一种具有新型作用机制的雌激素受体拮抗剂。
Br J Cancer. 2004 Mar;90 Suppl 1(Suppl 1):S2-6. doi: 10.1038/sj.bjc.6601629.
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Development of novel oestrogen-receptor antagonists.新型雌激素受体拮抗剂的研发。
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Hormone therapy for breast cancer, with an emphasis on the pure antiestrogen fulvestrant: mode of action, antitumor efficacy and effects on bone health.乳腺癌的激素治疗,重点是纯抗雌激素氟维司群:作用机制、抗肿瘤疗效及对骨骼健康的影响
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Fulvestrant: a review of its use in hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following antiestrogen therapy.氟维司群:用于抗雌激素治疗后疾病进展的绝经后激素受体阳性转移性乳腺癌女性患者的应用综述
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Effects of 4-hydroxytamoxifen and a novel pure antioestrogen (ICI 182780) on the clonogenic growth of human breast cancer cells in vitro.4-羟基他莫昔芬及新型纯抗雌激素药物(ICI 182780)对人乳腺癌细胞体外克隆生长的影响
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Estrogen induces death of tamoxifen-resistant MCF-7 cells: contrasting effect of the estrogen receptor downregulator fulvestrant.雌激素诱导他莫昔芬耐药的MCF-7细胞死亡:雌激素受体下调剂氟维司群的相反作用。
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The novel anti-oestrogen idoxifene inhibits the growth of human MCF-7 breast cancer xenografts and reduces the frequency of acquired anti-oestrogen resistance.新型抗雌激素药物艾多昔芬可抑制人MCF-7乳腺癌异种移植瘤的生长,并降低获得性抗雌激素耐药的发生率。
Br J Cancer. 1997;75(6):804-9. doi: 10.1038/bjc.1997.144.