[Microalbuminuria in diabetics treated with insulin for more than 30 years].

Microalbuminuria was determined in the urine of 6 diabetics who had been treated with Insulin for over 30 years an had a normal kidney function. The values gained by the radial immunodiffusion method (VLC--Partigen Albumin) range from 0.001 gr/l to 0.008 gr/l of albumins in the urine. These values are much below the risky ones (over 0.020 gr/l), which signalize the evolution to the macroproteinuria and the development of the diabetic nephropathy. Over 30 years duration of the insulin-dependent diabetes, with no macroproteinuria pretors on the expression of diabetic nephropathy. 5 locus which is known to have the influence on the intensity of the immunological response.