Meltzer C C, Smirniotopoulos J G, Jones R V
Department of Radiology, University of Pittsburgh Medical Center, Pa.
Radiology. 1995 Mar;194(3):699-703. doi: 10.1148/radiology.194.3.7862965.
To correlate the magnetic resonance (MR) imaging features of and histologic findings in Lhermitte-Duclos disease (LDD) (dysplastic gangliocytoma).
MR imaging and histologic data from eight patients with the diagnosis of LDD were retrospectively reviewed. Gross pathologic specimens were also available in one case. Contrast material-enhanced MR images were obtained in seven of the eight patients.
At MR imaging, a non-enhancing mass in the cerebellar hemisphere was characterized by a striated pattern of hyperintensity on T2-weighted images and corresponding hypointensity on T1-weighted images, which represented the abnormally thickened folia. None of the masses demonstrated enhancement.
Most other cerebellar masses destroy the folial pattern and show enhancement. The nonenhancing striated MR appearance of thickened folia in patients with LDD is distinctive and should suggest this diagnosis.
探讨Lhermitte-Duclos病（LDD，发育异常性神经节细胞瘤）的磁共振（MR）成像特征与组织学表现之间的相关性。
回顾性分析8例诊断为LDD患者的MR成像及组织学资料。8例患者中有1例可获取大体病理标本。8例患者中有7例行对比剂增强MR成像检查。
在MR成像上，小脑半球的无强化肿块在T2加权像上表现为有条纹状的高信号，在T1加权像上相应为低信号，代表异常增厚的脑叶。所有肿块均无强化。
大多数其他小脑肿块会破坏脑叶形态并显示强化。LDD患者增厚脑叶的无强化条纹状MR表现具有特征性，应提示该诊断。
