A surgically treated case of Lhermitte-Duclos disease with a precise natural history and high uptake of FDG on PET.

We describe herein a surgically treated case of Lhermitte-Duclos disease in a 33-year-old man. The clinical presentation seemed typical in terms of symptoms, neurological signs, and neuroimaging. High and heterogenous fluorodeoxyglucose uptake in positron emission tomography study is presented and discussed. Furthermore, we performed volumetric analysis of the tumor with sequential magnetic resonance imaging over the course of 7 years before surgery, making this report the first with a long-term natural history, revealing that this rare disease entity may have a neoplastic nature.