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[通过电视数据的时间序列分析对新型抗抑郁药(维洛沙嗪)的研究]

[Studies on a novel antidepressant (viloxazin) by means of time-series analysis of TV data].

作者信息

Renfordt E, Busch H, Fähndrich E, Müller-Oerlinghausen B

出版信息

Arzneimittelforschung. 1976;26(6):1114-6.

PMID:786309
Abstract

19 depressed patients were treated with viloxazin (n = 9) or amitriptyline (n = 10) in a double-blind-trial. TV-tapes were produced for each patient on day 0, 10 and 20. These tapes were analysed with respect to the intensity of depression by 4 independent raters under the condition of a time-blind analysis. These 3 TV-tapes could easily be discriminated in the sense of a decreasing depressivity. The results suggest that the effect of viloxazin has a shorter delay than that of amitriptyline.

摘要

19名抑郁症患者在双盲试验中接受了维洛沙嗪(n = 9)或阿米替林(n = 10)治疗。在第0天、第10天和第20天为每位患者制作了录像带。这些录像带由4名独立评估者在时间盲分析的条件下,根据抑郁强度进行分析。从抑郁程度降低的意义上来说,这3部录像带很容易区分。结果表明,维洛沙嗪的起效延迟比阿米替林短。

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