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冠状动脉搭桥手术期间的再灌注心室颤动及电击除颤——与术后肌酸激酶同工酶(CK-MB)释放的相关性

Reperfusion ventricular fibrillation and electric countershocks during coronary artery bypass operations--association with postoperative CK-MB release.

作者信息

Hippeläinen M J, Tuppurainen T T, Huttunen K T

机构信息

Department of Surgery, Kuopio University Hospital, Finland.

出版信息

Scand J Thorac Cardiovasc Surg. 1994;28(2):73-8. doi: 10.3109/14017439409100166.

Abstract

Reperfusion ventricular fibrillation during coronary artery bypass surgery is common and electric shocks are often needed to terminate it. Both the fibrillation and the reversing electric shocks are potentially detrimental to the myocardium. In 61 aortocoronary bypass patients with uncomplicated clinical course (no difficulties in weaning from bypass, no ECG changes and no inotropic medication), serial creatine kinase-MB values were recorded. Evaluated explanatory variables were patient age, ejection fraction, aortic occlusion time, perfusion time, number of peripheral anastomoses and of anastomoses to marginal branches, myocardial fibrillation time before aortic cross-clamping, after cross-clamping prior to cardiac arrest and after declamping, and number of defibrillations. The results indicated that reperfusion fibrillation times up to 10 minutes are not harmful, provided that left ventricular decompression is carried out. Too early and thus numerous defibrillations raise creatine kinase-MB levels and probably also damage the myocardium, and therefore should be avoided.

摘要

冠状动脉搭桥手术期间的再灌注室颤很常见,通常需要电击来终止。室颤和反向电击都可能对心肌有害。在61例临床过程无并发症(脱离体外循环无困难、无心电图改变且未使用正性肌力药物)的主动脉冠状动脉搭桥患者中,记录了肌酸激酶-MB的系列值。评估的解释变量包括患者年龄、射血分数、主动脉阻断时间、灌注时间、外周吻合口数量以及与边缘分支的吻合口数量、主动脉阻断前、心脏停搏前交叉阻断后以及松开阻断后心肌颤动时间,以及除颤次数。结果表明,只要进行左心室减压,再灌注颤动时间长达10分钟并无危害。过早且频繁的除颤会提高肌酸激酶-MB水平,可能还会损害心肌,因此应避免。

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