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心肌肌钙蛋白T快速检测法在诊断电复律继发心肌损伤中的应用。

Use of cardiac troponin T rapid assay in the diagnosis of a myocardial injury secondary to electrical cardioversion.

作者信息

Garré L, Alvarez A, Rubio M, Pellegrini A, Caridi M, Berardi A, Lázzaro C, Blanco P, Menehem C, Díaz M

机构信息

Coronary Care Unit, Hospital Naval Pedro Mallo, Buenos Aires, Argentina.

出版信息

Clin Cardiol. 1997 Jul;20(7):619-21. doi: 10.1002/clc.4960200707.

Abstract

BACKGROUND AND HYPOTHESIS

This study was carried out to determine whether cardiac troponin T test in rapid assay gives positive results in patients previously submitted to cardioversion or electrical defibrillation.

METHODS

Forty patients with supraventricular tachyarrhythmias lasting no more than 2 days were treated with electrical cardioversion. The total creatine phosphokinase (CPK)-MB isoenzyme and troponin T in rapid assay were measured at baseline and at 6, 12, and 24 h thereafter.

RESULTS

Total CPK baseline levels were normal in all cases; within 4 h, the serum CPK levels increased by 98%, at 6 h by 111.5%, at 12 h by 168%, and at 24 h by 225% (p > 0.01). The CPK-MB isoenzyme showed no percentage increase of total CPK higher than 5%, measured at 6, 12, and 24 h after the shock, independent of the number of attempts of cardioversion. The troponin T test was also negative in all cases at baseline and at 6, 12, and 24 h after cardioversion.

CONCLUSION

We conclude that the absence of elevations in CPK-MB levels and cardiac troponin T levels matched clinical and electrocardiographic results showing absence of myocardial damage after electrical cardioversion.

摘要

背景与假设

本研究旨在确定快速检测心肌肌钙蛋白T试验对既往接受过心脏复律或电除颤的患者是否呈阳性结果。

方法

40例室上性快速心律失常持续不超过2天的患者接受了心脏电复律治疗。在基线时以及此后6、12和24小时测量总肌酸磷酸激酶(CPK)-MB同工酶和快速检测的肌钙蛋白T。

结果

所有病例的总CPK基线水平均正常;4小时内,血清CPK水平升高了98%,6小时时升高了111.5%,12小时时升高了168%,24小时时升高了225%(p>0.01)。在电击后6、12和24小时测量,CPK-MB同工酶占总CPK的百分比升高不超过5%,与心脏复律的尝试次数无关。在基线时以及心脏复律后6、12和24小时,肌钙蛋白T试验在所有病例中也均为阴性。

结论

我们得出结论,CPK-MB水平和心肌肌钙蛋白T水平未升高与临床和心电图结果相符,表明心脏电复律后无心肌损伤。

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